Semen analysis is the most common way for male fertility diagnosis, in which parameters including sperm concentration, motility, morphology and etc are assessed. Statistics showed that male factors accounted for around 30% of infertility cases.
 
Semen Assessment (SA) - Based on WHO manual 2010
Semen Assessment (SA) - Based on WHO manual 2010
Intrauterine insemination refers to placing sperm into a woman's uterine cavity in order to facilitate fertilization. Patient must have patent fallopian tubes to allow fertilization to take place inside the body.
 
Broadly speaking, it involves the following steps: ovarian stimulation (2-3 follicles), sperm processing and intra-uterine insemination (IUI). This is a non-invasive fertility treatment, with the least complications whilst an acceptable success rate of around 15%.
 
Indications: 
  • Unexplained infertility
  • Male infertility (mild)
  • Ejaculatory failure
  • Retrograde ejaculation
  • Hostile cervical condition
Sperm Preparation for Intra-Uterine Insemination (IUI)
Sperm Preparation for Intra-Uterine Insemination (IUI)
ICSI is the most recent medical breakthrough in treating male infertility. The procedure involves injecting a sperm into an egg using a very fine needle under microscope, the fertilized egg will then be cultured into embryo and be prepared for transfer.

Indications:
  • Male infertility
  • Failed or poor fertilization from previous IVF cycle
  • Pre-implantation genetic diagnosis
Intra-Cytoplasmic Sperm Injection (ICSI)
Intra-Cytoplasmic Sperm Injection (ICSI)
In order for an embryo to be implanted, it must escaped from its zona pellucida (the shell). Laser assisted hatching is a technique that involves creating a small hole in the zona pellucida using laser, hence increasing the implantation rate. 
 
Indications: 
  • Advanced maternal age ≥ 38 
  • Repeated implantation failure
  • Embryos with thick or abnormal zona pellucida 
Laser Assisted Hatching (LAH)
Laser Assisted Hatching (LAH)
Preimplantation Genetic Screening (PGS) is the genetic test used to screen the health status of embryos before they are transferred to the uterus in an IVF cycle. Many embryos look normal but have the wrong number of chromosomes (called aneuploidy) and cannot give rise to a normal pregnancy. PGS offers a better embryo selection for transfer, hence increasing the chance of having normal live baby.  
 
Indications: 
  • Advanced maternal age 
  • Recurrent miscarriage
  • Repeated implantation failure
  • Previous repeated abnormal pregnancies
  • Severe male factor infertility
  • Couples who are carriers of a chromosomal disorder
Preimplantation Genetic Screening (PGS)
Preimplantation Genetic Screening (PGS)
Blastocyst culturing is referring to the extended culturing of embryos to blastocyst stage, normally on the fifth day after oocyte retrieval. Extended culturing helps to select the embryo with best implantation potential for transfer, maximising the pregnancy rates while minimising the risk of multiple pregnancies.
 
Indications:
  • High number of embryos produced
  • Multiple pregnancies have to be avoided (e.g. malformed uterus)
Blastocyst Transfer
Blastocyst Transfer
Cryopreservation allows banking of surplus embryos for later use. The embryos are stored in liquid nitrogen at -196ºC.

Vitrification is the most up-to-date freezing technique which provides the highest frozen-thaw survival rate (>90%) and causes the least damage to the embryos.

Embryo Banking (Embryo Freezing)
Embryo Banking (Embryo Freezing)
We provide gamete (sperm/egg) freezing and storage service to couples who are receiving infertility treatment, and for patients who may be rendered infertile due to upcoming surgery or medical treatment.

Sperm Banking and Oocyte Banking
Sperm Banking and Oocyte Banking
This is a minor surgery done to retrieve sperm from azoospermic men – men who have no sperm in their semen. There is a 50-90% chance of sperm being successfully retrieved. The retrieved sperm will be used in Intra-Cytoplasmic Sperm Injection (ICSI) treatment. 
 
Indications:
  • Obstructive azoospermia, eg: Vas deferens or epididymal obstruction 
  • Non-obstructive azoospermia, eg: Testicular failure
  • Inability to ejaculate
  • Vasectomy 
The sperm can be retrieved from the epididymis (the site of temporary sperm storage) or the testicle (the site of sperm production), using 4 techniques below: 
 
PESA (Percutaneous Epididymal Sperm Aspiration) 
This technique can be applied for men with obstructive azoospermia. A small needle is placed into epididymis and simply aspirate fluid inside epididymis. This fluid will be assessed for presence of sperm.
 
MESA (Microsurgical Epididymal Sperm Aspiration) 
This technique can be applied for men with obstructive azoospermia. An operating microscopy is used to locate the tubules of epididymis precisely so large numbers of sperm can be retrieved. The aspirated fluid will be assessed for presence of sperm. 
 
TESA (Testicular Sperm Aspiration) 
This technique can be applied for men with obstructive azoospermia. A small needle is placed into testicle and simply aspirate fluid inside testicle.  This fluid will be assessed for presence of sperm.
 
TESE (Testicular Sperm Extraction) 
This technique can be applied for men with non-obstructive azoospermia. A small incision is made in the scrotal skin and testicular tissues from several regions of the testicle are biopsied. The biopsied tissues are processed and assessed for presence of sperm. 
 
Surgical Sperm Retrieval (SSR)
Surgical Sperm Retrieval (SSR)
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